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Name: Dr. Gul Shahnaz
Designation: Professor (Tenured), Ex-Chairperson
Department: Pharmacy


Qualifications: PhD (Pharmaceutical Technology) Austria, Post Doc (USA)


Phone: +92-51 9064-4137
Email: gshahnaz@qau.edu.pk
Status: On job
Other Weblink: https://scholar.google.com.pk/citations?user=KaTRdF4AAAAJ&hl=en

View Resume

Research Interests Publications Conferences Research Projects

Advanced Drug Delivery Systems:

    • Developing innovative nanocarriers and biomaterials for targeted drug delivery to enhance therapeutic efficacy and reduce side effects.
    • Exploring the potential of stimuli-responsive drug delivery systems for precise control of drug release.
    • Integrating artificial intelligence and machine learning to optimize drug delivery system design and formulation.

Combating Antimicrobial Resistance:

    • Designing novel antimicrobial agents and delivery systems to overcome bacterial resistance mechanisms.
    • Investigating the role of the immune system in antimicrobial resistance and developing immunomodulatory strategies.
    • Developing combination therapies and synergistic approaches to combat multidrug-resistant infections.

Cancer Therapeutics:

    • Developing targeted therapies for cancer, including antibody-drug conjugates, nanoparticle-based drug delivery systems, and cancer vaccines.
    • Investigating the role of the tumor microenvironment in cancer progression and developing strategies to target it.
    • Exploring the potential of personalized medicine and precision oncology in cancer treatment.

Neglected Tropical Disease Prevention:

    • Developing affordable and effective drug delivery systems for neglected tropical diseases, particularly in resource-limited settings.
    • Investigating the role of vector control and public health interventions in preventing and controlling neglected tropical diseases.
    • Developing novel vaccines and immunotherapies for neglected tropical diseases.

Emerging Research Interests:

  • Immunotherapy and Cancer Immunotherapy:
    • Developing immune checkpoint inhibitors and other immunotherapies to enhance the body’s natural defenses against cancer.
    • Investigating the role of the microbiome in cancer immunotherapy and developing strategies to modulate it.
  • Digital Health and Personalized Medicine:
    • Developing personalized medicine approaches to tailor drug therapy to individual patients based on their genetic and molecular profiles.

 Impact Factor ~350, Citation: 3356, h-index: 42, i10-index: 64

1.      Balquis, F., Sohail, M. F., Hamid, H., Ullah, W., Khan, A. H., & Shahnaz, G. (2023). Potential and weak links in the management of tuberculosis by Pakistani private pharmacy staff. Frontiers in Public Health, 11, 983997. https://doi.org/10.3389/fpubh.2023.983997 (Impact Factor: 5.18) - Category: W

2.      Ahmed, N., Sohail, M. F., Khurshid, Z., et al. (2023). Synthesis, characterization, and in vivo distribution of 99mTc radiolabeled docetaxel-loaded folic acid-thiolated chitosan enveloped liposomes. BioNanoScience, 13, 134–144. https://doi.org/10.1007/s12668-022-00953-0 (Impact Factor: 3.63) - Category: W

3.      Shakeel, M., Kiani, M. H., Sarwar, H. S., Akhtar, S., Rauf, A., Ibrahim, I. M., Ajalli, N., Shahnaz, G., Rahdar, A., & Díez-Pascual, A. M. (2023). Emulgel-loaded mannosylated thiolated chitosan-coated silver nanoparticles for the treatment of cutaneous leishmaniasis. International Journal of Biological Macromolecules, 227, 1293-1304. https://doi.org/10.1016/j.ijbiomac.2022.07.042 (Impact Factor: 8.025) - Category: W

4.      Zahra, T., Sarwar, H. S., Sarfraz, M., Zaman, M., Ahmad, H., Jalil, A., Shahnaz, G., & Sohail, M. F. (2022). Thiomer-coated solid lipid nanoparticles for enhanced oral bioavailability of tacrolimus: In vitro and in vivo evaluation. Journal of Drug Delivery Science and Technology, 67, 102921. https://doi.org/10.1016/j.jddst.2022.102921 (Impact Factor: 5.062) - Category: W

5.      Kiani, M., et al. (2022). Cholesterol-decorated thiolated stereocomplexed nanomicelles for improved anti-mycobacterial potential via efflux pump and mycothione reductase inhibition. Journal of Molecular Liquids, 349, 118639. https://doi.org/10.1016/j.molliq.2022.118639 (Impact Factor: 6.16) - Category: W

6.      Qaisar, A. (2022). Design and synthesis of multifunctional polymeric micelles for targeted delivery in Helicobacter pylori infection. Journal of Molecular Liquids, 348, 118652. https://doi.org/10.1016/j.molliq.2022.118652 (Impact Factor: 6.16) - Category: W

7.      Arshad, R., Arshad, M. S., Tabish, T. A., Shah, S. N. H., Afzal, S., & Shahnaz, G. (2022). Amidated Pluronic decorated muco-penetrating self-nano emulsifying drug delivery system (SNEDDS) for improved anti-Salmonella typhi potential. Pharmaceutics, 14(11), 2433. https://doi.org/10.3390/pharmaceutics14112433 (Impact Factor: 5.55) - Category: W

8.      Jahan, F., Zaman, S. U., Syed, M. A., Arshad, R., Amjad, O., Ali, I., Gul, R., Shahnaz, G., Aamir, M. N., & Hanif, S. (2022). HPLC method development and validation for in vitro and in vivo quantification of vancomycin in rabbit plasma. Pakistan Journal of Pharmaceutical Sciences, 35(6(Special)), 1683-1690. https://doi.org/10.1007/s00216-022-03785-3 (Impact Factor: 0.79) - Category: W

9.      Shahid, S., Ahmed, F., Shahnaz, G., Saqlain, M., Ans, M., & Sana, A. (2022). The impact of theoretical and practical guidance regarding metered dose inhaler technique on asthma patients. Journal of Young Pharmacists, 14(3), 327-332. https://doi.org/10.4103/jyp.jyp_13_22 - Category: W

10.   Nazir, F., Tabish, T. A., Tariq, F., Iftikhar, S., Wasim, R., & Shahnaz, G. (2022). Stimuli-sensitive drug delivery systems for site-specific antibiotic release. Drug Discovery Today, 27(6), 1698-1705. https://doi.org/10.1016/j.drudis.2022.02.005 (Impact Factor: 8.369) - Category: W

11.   Javed QUA, Syed MA, Arshad R, Rahdar A, Irfan M, Raza SA, Shahnaz G, Hanif S, Díez-Pascual AM. Evaluation and Optimization of Prolonged Release Mucoadhesive Tablets of Dexamethasone for Wound Healing: In Vitro-In Vivo Profiling in Healthy Volunteers. Pharmaceutics, 2022 Apr 7; 14(4):807. Impact Factor: 6.525.

12.   Habib, R., Azad, A.K., Akhlaq, M., Al-Joufi, F.A., Shahnaz, G., Mohamed, H.R.H., Naeem, M., Almalki, A.S.A., Asghar, J., Jalil, A., Abdel-Daim, M.M. Thiolated Chitosan Microneedle Patch of Levosulpiride from Fabrication, Characterization to Bioavailability Enhancement Approach. Polymers, 2022; 14:415. Impact Factor: 4.967.

13.   Razzaq, S., Rauf, A., Raza, A., Akhtar, S., Tabish, T.A., Sandhu, M.A., Zaman, M., Ibrahim, I.M., Shahnaz, G., Rahdar, A., Díez-Pascual, A.M. A Multifunctional Polymeric Micelle for Targeted Delivery of Paclitaxel by the Inhibition of the P-Glycoprotein Transporters. Nanomaterials, 2021; 11:2858. Impact Factor: 5.719.

14.   Rauf A, Tabish TA, Tehseen S, Sandhu MA, Pandey S, Shahnaz G, Rahdar A. Design of Mannose-Coated Rifampicin Nanoparticles Modulating the Immune Response and Rifampicin Induced Hepatotoxicity with Improved Oral Drug Delivery. Arab. J. Chem., 2021. Impact Factor: 5.16.

15.   Kiani MH, Ali S, Qadry A, Arshad R, Aslam A, Shahnaz G. Polyethylene imine conjugated supramolecular stereocomplexed nanomicelles for intracellular delivery of rifampicin against Mycobacterium bovis. Colloids Surf. B, 2021. Impact Factor: 5.26.

16.   Razzaq S, Rauf A, Tabish TA, Raza A, Shahnaz G. Papain decorated multi‐functional polymeric micelles for the targeted intracellular delivery of paclitaxel. Polymer for Advanced Technologies, 2021. Impact Factor: 3.66.

17.   Arshad R, Tabish TA, Kiani MH, Ibrahim MI, Shahnaz G, Rahdar A, Kang M, Pandey S. A Hyaluronic Acid Functionalized Self-NanoEmulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection. Nanomaterials, 2021 May; 14(4):387-406. Impact Factor: 5.06.

18.   Arshad A, Tabish TA, Naseem AA, Hassan AB, Hussain I, Hussain Shahzad, Shahnaz G. Development of poly-L-lysine multi-functionalized muco-penetrating self-emulsifying drug delivery system (SEDDS) for improved solubilization and targeted delivery of ciprofloxacin against intracellular Salmonella typhi. J. Mol. Liq., 2021. Impact Factor: 6.16.

19.   Iqbal R, Yousaf MA, Sohail MF, Rehman M, Hussain SZ, Huma Z, Shahnaz G, Quereshi OS, Shahnaz G. Enhanced solubility and biopharmaceutical performance of atorvastatin and metformin via electrospun polyvinylpyrrolidone-hyaluronic acid composite nanoparticles. Eur. J. Pharm. Sci., 2021. Impact Factor: 3.616.

20.   Arshad R, Paul K, Sabir F, Rahdar A, Bilal M, Shahnaz G, Kyzas. A review of nanomaterial use for the diagnosis and therapy of Salmonella typhi. J. Mol. Struct., 2021. Impact Factor: 3.16.

21.   Jahan F, Zaman S, Arshad R, Tabish TA, Shahnaz G. Mapping the potential of thiolated pluronic-based nanomicelles for the safe and targeted delivery of vancomycin against staphylococcal blepharitis. J. Drug Deliv. Sci. Technol., 2021. Impact Factor: 3.96.

22.   Rauf A, Razzaq S, Tabish TA, Tehseen S, Sandhu MA, Shahnaz G. Investigating the intracellular bactericidal effects of rifampicin loaded S-protected thiomeric chitosan nanocargoes against Mycobacterium tuberculosis. J. Drug Deliv. Sci. Technol., 2020. Impact Factor: 3.96.

  1. Fabrication and optimization of pH-sensitive mannose-anchored nanovehicle as a promising approach for macrophage uptake. Mukhtar A, Zeeshan M, Khan S, Shahnaz G, Khan SA, Sarwar HS, Pasha RA, Ali H. Applied Nanoscience, ISSN: 1388-0764, 2020, IF: 3.66.
  2. Green synthesized selenium-doped zinc oxide nano antibiotics: Synthesis, characterization, and evaluation of antimicrobial, nanotoxicity, and teratogenicity potential. Sohail MF, Rehman M, Hussain SZ, Huma Z, Shahnaz G, Qureshi OS, Khalid Q, Hussain I. J. Mater. Chem. B, ISBN: 2050-750X, IF: 4.889.
  3. Green synthesis of zinc oxide nanoparticles by neem extract as multi-facet therapeutic agents. Sohail MF, Rehman M, Hussain SZ, Huma Z, Shahnaz G, Qureshi OS, Khalid Q, Hussain I. J Drug Deliv Sci Technol, ISSN: 1773-2247, 2020, IF: 6.3.
  4. Amphotericin B-loaded polymeric nanoparticles for treatment of Leishmania infections. Saqib M, Bhatti S, Ahmad N, Ahmed N, Shahnaz G, Lebaz N. Nanomaterials, ISSN: 1743-5889, Feb 2020; 14(4):387-406, IF: 3.96.
  5. Oral delivery and enhanced efficacy of antimonal drug through macrophage-guided multifunctional nanocargoes against visceral leishmaniasis. Sarwar HS, Varikuti S, Sohail MF, Sarwar MS, Satoskar AR, Shahnaz G. Eur J Pharm Biopharm, 79(1):171-80, IF: 5.06.
  6. Synthesis and characterization of pre-activated thiolated chitosan nanoparticles for oral delivery of octreotide. Maria S, Sarwar HS, Sohail MF, Imran M, Salman O, Ahmad N, Iqbal A, Shahnaz G. J Drug Deliv Sci Technol, ISSN: 1773-2247, 2020, IF: 4.604.
  7. Multi-functionalized nanocarriers targeting bacterial reservoirs to overcome challenges of multi-drug resistance. Kiani MH, Imran M, Raza A, Shahnaz G. DARU J. Pharm. Sci., ISSN: 1773-2247, 2020, IF: 3.96.
  8. Formulation and evaluation of hyaluronic acid-based mucoadhesive self-nanoemulsifying drug delivery system (SNEDDS) of tamoxifen for targeting breast cancer. Batool A, Khan R, Razzaq S, Nousheen K, Kiani MH, Shahnaz G. Int J Biol Macromol, ISSN: 1773-2247, 2020, IF: 3.117.
  9. Fabrication and characterization of thiolated chitosan microneedle patch for transdermal delivery of tacrolimus. Ahmad Z, Khan MA, Siddiqui MI, Sarwar HS, Sohail MF, Rehman M, Hussain I, Shahnaz G. AAPS PharmSciTech, ISSN: 1530-9932, 2020; 21(2):60, IF: 3.2.
  10. Design of enzyme-decorated mucopermeating nanocarriers for eradication of H. pylori infection. Zafar H, Kiani MH, Raza F, Rauf A, Chaudhery I, Ahmad NM, Akhtar S, Shahnaz G. J Nanoparticle Res., ISSN: 1388-0764, 2020, IF: 2.
  11. Development and characterization of bioadhesive film embedded with lignocaine and calcium fluoride nanoparticles. Ghafar H, Khan MI, Sarwar HS, Yaqoob S, Hussain SZ, Tariq I, Madni AU, Shahnaz G, Sohail MF. AAPS PharmSciTech, ISSN: 1530-9932, 2020; 21(2):60, IF: 3.2.
  12. Formulation and evaluation of novel thiolated intra-pocket periodontal composite membrane of doxycycline. Kanwal A, Iqbal A, Arshad R, Akhtar S, Razzaq S, Ahmad NM, Naz H, Shahnaz G. AAPS PharmSciTech, ISSN: 1530-9932, 2019; 20(8):325, IF: 3.2.
  13. Development and evaluation of optimized thiolated chitosan proniosomal gel containing duloxetine for intranasal delivery. Khatoon M, Sohail MF, Shahnaz G, Rehman F, Din FU, Rehman AU. Journal name, Year (IF).
  14. ZnO-NPs embedded biodegradable thiolated bandage for postoperative surgical site infection: In vitro and in vivo evaluation. Arshad R, Sohail MF, Sarwar HS, Saeed H, Ali I, Akhtar S, Hussain SZ, Afzal A, Jehan J, Rehman A, Shahnaz G. AAPS PharmSciTech, ISSN: 1530-9932, 2019; 18(4):1043-1055. Also published in PLOS ONE, ISSN: 1932-6203, 2019, IF: 3.2.
  15. Drug delivery system (SNEDDS) for improved oral bioavailability of chlorpromazine: In vitro and in vivo evaluation. Baloch J, Sohail MF, Sarwar HS, Kiani MH, Khan GM, Jahan S, Rafay M, Chaudhry MT, Yasinzai M, Shahnaz G. Medicina (Kaunas), ISSN: 1010-660X, May 2019; 55(5), IF: 2.43.
  16. Mannosylated thiolated paromomycin-loaded PLGA nanoparticles for the oral therapy of visceral leishmaniasis. Afzal I, Sarwar HS, Sohail MF, Varikuti S, Jahan S, Akhtar S, Yasinzai M, Satoskar AR, Shahnaz G. Nanomedicine (Lond), ISSN: 1743-5889, Feb 2019; 14(4):387-406, IF: 5.3.
  17. Folate-functionalized thiomeric nanoparticles for enhanced docetaxel cytotoxicity and improved oral bioavailability. Sajjad M, Khan MI, Naveed S, Ijaz S, Qureshi OS, Raza SA, Shahnaz G, Sohail MF. AAPS PharmSciTech, ISSN: 1530-9932, Jan 2019; 20(2):81, IF: 3.2.
  18. Evaluation of turmeric nanoparticles as an anti-gout agent: Modernization of a traditional drug. Kiyani MM, Sohail MF, Shahnaz G, Rehman H, Akhtar MF, Nawaz I, Mahmood T, Manzoor M, Bokhari SAI. Medicina (Kaunas), ISSN: 1010-660X, Jan 2019; 55(1), IF: 2.43.
  19. Polymeric nanocapsules embedded with ultra-small silver nanoclusters for synergistic pharmacology and improved oral delivery of docetaxel. Sohail MF, Hussain SZ, Saeed H, Javed I, Sarwar HS, Nadhman A, Huma ZE, Rehman M, Jahan S, Hussain I, Shahnaz G. Sci Rep., ISSN: 2045-2322, Sep 2018; 8(1):13304, IF: 4.6.

42.   Sohail, M. F., Rehman, M., Sarwar, H. S., Naveed, S., Salman, O., Bukhari, N. I., Hussain, I., Webster, T. J., & Shahnaz, G. (2018). Advancements in the oral delivery of docetaxel: Challenges, current state-of-the-art, and future trends. International Journal of Nanomedicine, 13, 3145–3161. https://doi.org/10.2147/IJN.S166087

43.   Sarwar, H. S., Sohail, M. F., Saljoughian, N., Rehman, A. U., Akhtar, S., Nadhman, A., Yasinzai, M., Gendelman, H. E., Satoskar, A. R., & Shahnaz, G. (2018). Design of mannosylated oral amphotericin B nanoformulation: Efficacy and safety in visceral leishmaniasis. Artificial Cells, Nanomedicine, and Biotechnology, 46(1), 1–11. https://doi.org/10.1080/21691401.2018.1428242

44.   Sarwar, H. S., Ashraf, S., Akhtar, S., Sohail, M. F., Hussain, S. Z., Rafay, M., Yasinzai, M., Hussain, I., & Shahnaz, G. (2018). Mannosylated thiolated polyethylenimine nanoparticles for the enhanced efficacy of antimonial drug against leishmaniasis. Nanomedicine (London), 13(1), 25–41. https://doi.org/10.2217/nnm-2017-0210

45.   Ovais, M., Nadhman, A., Khalil, A. T., Raza, A., Khuda, F., Sohail, M. F., Islam, N. U., Sarwar, H. S., Shahnaz, G., Ahmad, I., Saravanan, M., & Shinwari, Z. K. (2017). Biosynthesized colloidal silver and gold nanoparticles as emerging leishmanicidal agents: An insight. Nanomedicine (London), 12(24), 2807–2819. https://doi.org/10.2217/nnm-2017-0275

46.   Sarwar, H. S., Akhtar, S., Sohail, M. F., Naveed, Z., Rafay, M., Nadhman, A., Yasinzai, M., & Shahnaz, G. (2017). Redox biology of Leishmania and macrophage targeted nanoparticles for therapy. Nanomedicine (London), 12(14), 1713–1725. https://doi.org/10.2217/nnm-2017-0071

47.   Sohail, M. F., Sarwar, H. S., Javed, I., Nadhman, A., Hussain, S. Z., Saeed, H., Raza, A., Bukhari, N. I., Hussain, I., & Shahnaz, G. (2017). Cell to rodent: Toxicological profiling of folate grafted thiomer enveloped nanoliposomes. Toxicological Research, 6, 814–821. https://doi.org/10.1039/C7TX00042A

48.   Shahnaz, G., Edagwa, B. J., McMillan, J., Akhtar, S., Raza, A., Qureshi, N. A., Yasinzai, M., & Gendelman, H. E. (2017). Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis. Nanomedicine (London), 12(2), 99–115. https://doi.org/10.2217/nnm-2016-0216

49.   Naz, K., Shahnaz, G., Ahmed, N., Qureshi, N. A., Sarwar, H. S., Imran, M., & Khan, G. M. (2017). Formulation and in vitro characterization of thiolated buccoadhesive film of fluconazole. AAPS PharmSciTech, 18(4), 1043–1055. https://doi.org/10.1208/s12249-016-0612-5

50.   Khan, H., Nadhman, A., Azam, S. S., Anees, M., Khan, I., Ullah, I., Sohail, M. F., Shahnaz, G., & Yasinzai, M. (2017). In-vitro antileishmanial potential of peptide drug hirudin. Chemical Biology & Drug Design, 89(1), 67–73. https://doi.org/10.1111/cbdd.12854

51.   Tahir, A. H., Tanveer, M., Ahmed, A., Arshad, A., & Shahnaz, G. (2016). Rise of single organopathy theory from Ayurveda system: A short report from Pakistan’s perspective. World Journal of Pharmaceutical Sciences, 5(12), 12–19.

52.   Sohail, M. F., Javed, I., Hussain, S. Z., Sarwar, H. S., Akhtar, S., Nadhman, A., Batool, S., Bukhari, N. I., Saleem, R. S. Z., Hussain, I., & Shahnaz, G. (2016). Folate grafted thiolated chitosan enveloped nanoliposomes with enhanced oral bioavailability and anticancer activity of docetaxel. Journal of Materials Chemistry B, 4, 6240–6248. https://doi.org/10.1039/C6TB01497A

53.   Nadhman, A., Khan, M. I., Nazir, S., Khan, M., Shahnaz, G., Raza, A., Shams, D. F., & Yasinzai, M. (2016). Annihilation of Leishmania by daylight responsive ZnO nanoparticles: A temporal relationship of reactive oxygen species-induced lipid and protein oxidation. International Journal of Nanomedicine, 11, 2451–2461. https://doi.org/10.2147/IJN.S106546

54.   Rauf, M. K., Shaheen, U., Asghar, F., Badshah, A., Nadhman, A., Azam, S., Ali, M. I., Shahnaz, G., & Yasinzai, M. (2016). Antileishmanial, DNA interaction, and docking studies of some ferrocene-based heteroleptic pentavalent antimonials. Archiv der Pharmazie (Weinheim), 349(1), 50–62. https://doi.org/10.1002/ardp.201500258

55.     Dünnhaupt, S., Barthelmes, J., Köllner, S., Sakloetsakun, D., Shahnaz, G., Düregger, A., & Bernkop-Schnürch, A. (2015). Thiolated nanocarriers for oral delivery of hydrophilic macromolecular drugs. Carbohydrate Polymers, 117, 577–584. https://doi.org/10.1016/j.carbpol.2014.10.035

56.   Javed, I., Hussain, S. Z., Ullah, I., Khan, I., Ateeq, M., Shahnaz, G., Rehman, H., Razi, M. T., Shah, M. R., & Hussain, I. (2015). Synthesis, characterization, and evaluation of lecithin-based nanocarriers for the enhanced pharmacological and oral pharmacokinetic profile of amphotericin B. Journal of Materials Chemistry B, 3(42), 8359–8365. https://doi.org/10.1039/C5TB00942A

57.   Nadhman, A., Nazir, S., Khan, M. I., Arooj, S., Bakhtiar, M., Shahnaz, G., & Yasinzai, M. (2014). PEGylated silver doped zinc oxide nanoparticles as novel photosensitizers for photodynamic therapy against Leishmania. Free Radical Biology and Medicine, 77, 230–238. https://doi.org/10.1016/j.freeradbiomed.2014.09.018

58.    Yasinzai, M., Khan, M., Nadhman, A., & Shahnaz, G. (2013). Drug resistance in leishmaniasis: Current drug-delivery systems and future perspectives. Future Medicinal Chemistry, 5(15), 1877–1888. https://doi.org/10.4155/fmc.13.139

59.   Development and in vitro evaluation of slippery nanoparticles for enhanced diffusion through native mucus Laffleur F, Hintzen F, Shahnaz G, Rahmat D, Leithner K, Bernkop-Schnürch A.
Nanomedicine (Lond.) 2014; 9(3):387-96. Impact Factor: 4.727

60.   Design and in vitro evaluation of a novel polymeric excipient for buccal applications
Laffleur F, Shahnaz G, Islambulchilar Z, Bernkop-Schnürch A. Future Med Chem. 2013; 5(5):511-22. Impact Factor: 3.556

61.   Development of thiolated poly(acrylic acid) microparticles for the nasal administration of exenatide Millotti G, Vetter A, Leithner K, Sarti F, Shahnaz G, Augustijns P, Bernkop-Schnürch A. Drug Dev Ind Pharm. 2014; 40(12):1677-82.
Impact Factor: 2.101

62.   Organotin(IV) complexes of carboxylate derivative as potential chemotherapeutic agents against Leishmania Qureshi QAH, Nadhman A, Sirajuddin M, Shahnaz G, Ali S, Shah A, Yasinzai M. Inorganica Chimica Acta 2014; 423(Part B):220-228. Impact Factor: 2.064

63.   Efficient MRI labeling of endothelial progenitor cells: design of thiolated surface stabilized superparamagnetic iron oxide nanoparticles Shahnaz G, Kremser C, Reinisch A, Vetter A, Laffleur F, Rahmat D, Iqbal J, Dünnhaupt S, Salvenmoser W, Tessadri R, Griesser U, Bernkop-Schnürch A. Eur J Pharm Biopharm. 2013; 85(3 Pt A):346-55. Impact Factor: 4.159

64.   Thiolated hydroxyethyl cellulose: design and in vitro evaluation of mucoadhesive and permeation enhancing nanoparticles Rahmat D, Müller C, Barthelmes J, Shahnaz G, Martien R, Bernkop-Schnürch A. Eur J Pharm Biopharm. 2013; 83(2):149-55. Impact Factor: 4.159

65.   Enzymatic degradation of thiolated chitosan
Laffleur F, Hintzen F, Rahmat D, Shahnaz G, Millotti G, Bernkop-Schnürch A.
Drug Dev Ind Pharm. 2013; 39(10):1531-9. Impact Factor: 2.101

66.   HEC-cystamine particles: influence of particle size, zeta potential, morphology and sulfhydryl groups on permeation enhancing properties
Rahmat D, Müller C, Shahnaz G, Leithner K, Laffleur F, Khan MI, Martien R, Bernkop Schnürch A. Drug Dev Ind Pharm. 2013; 39(9):1338-45. Impact Factor: 2.101

67.   Thiomers: influence of molar mass on in situ gelling properties
Hintzen F, Laffleur F, Sarti F, Shahnaz G, Bernkop-Schnürch. Int J Pharm. 2012; 436(1-2):120-6. Impact Factor: 3.694

68.   Thiolated chitosan nanoparticles for the nasal administration of leuprolide: bioavailability and pharmacokinetic characterization
Shahnaz G, Vetter A, Barthelmes J, Rahmat D, Laffleur F, Iqbal J, Perera G, Schlocker W, Dünnhaupt S, Augustijns P, Bernkop-Schnürch A. Int J Pharm. 2012; 428(1-2):164-7 Impact Factor: 3.694

69.   Synergistic effects of conjugating cell penetrating peptides and thiomers on non-viral transfection efficiency Rahmat D, Khan MI, Shahnaz G, Sakloetsakun D, Perera G, Bernkop-Schnürch A. Biomaterials 2012; 33(7):2321-6. Impact Factor: 8.402

70.   Preactivated thiomers as mucoadhesive polymers for drug delivery Iqbal J, Shahnaz G, Dünnhaupt S, Müller C, Hintzen F, Bernkop-Schnürch A. Biomaterials 2012; 33(5):1528-35. Impact Factor: 8.402

71.   HEC-cysteamine conjugates: influence of degree of thiolation on efflux pump inhibitory and permeation enhancing properties
Rahmat D, Sakloetsakun D, Shahnaz G, Sarti F, Laffleur F, Bernkop-Schnürch A.
Int J Pharm. 2012; 422(1-2):40-6. Impact Factor: 3.694

72.   Development and in vivo characterization of a novel peptide drug delivery system providing extended plasma half-life
Shahnaz G, Iqbal J, Rahmat D, Perera G, Laffleur F, Rossi D, Bernkop-Schnürch A.
J Control Release 2012; 157(3):375-82. Impact Factor: 7.786

73.   Sarti, F., Iqbal, J., Müller, C., Shahnaz, G., Rahmat, D., & Bernkop-Schnürch, A. (2012). Poly(acrylic acid)-cysteine for oral vitamin B12 delivery. Analytical Biochemistry, 420(1), 13–19.

74.   Iqbal, J., Shahnaz, G., Perera, G., Hintzen, F., Sarti, F., & Bernkop-Schnürch, A. (2012). Thiolated chitosan: Development and in vivo evaluation of an oral delivery system for leuprolide. European Journal of Pharmaceutics and Biopharmaceutics, 80(1), 95–102.

75.   Rahmat, D., Sakloetsakun, D., Shahnaz, G., Perera, G., Kaindl, R., & Bernkop-Schnürch, A. (2011). Design and synthesis of a novel cationic thiolated polymer. International Journal of Pharmaceutics, 411(1–2), 10–17.

76.   Shahnaz, G., Hartl, M., Barthelmes, J., Leithner, K., Sarti, F., Hintzen, F., Rahmat, D., Salvenmoser, W., & Bernkop-Schnürch, A. (2011). Uptake of phenothiazines by the harvested chylomicrons ex vivo model: Influence of self-nanoemulsifying formulation design. European Journal of Pharmaceutics and Biopharmaceutics, 79(1), 171–180.

77.   Murtaza, G., Ahmad, M., & Shahnaz, G. (2010). Microencapsulation of diclofenac sodium by non-solvent addition technique. Tropical Journal of Pharmaceutical Research, 9(2), 187–195.

78.   Shahnaz, G., Perera, G., Sakloetsakun, D., Rahmat, D., & Bernkop-Schnürch, A. (2010). Synthesis, characterization, mucoadhesion, and biocompatibility of thiolated carboxymethyl dextran-cysteine conjugate. Journal of Controlled Release, 144(1), 32–38. 

1)   

  1. 5th Annual Meeting Center for Molecular Biosciences (CMBI), 26–27 June 2008, Igls, Tyrol, Austria.
  2. Life Science Meeting, 18–19 September 2009, Igls, Tyrol, Austria.
  3. EuroNanoMedicine Conference, 28–30 September 2009, Bled, Slovenia.
  4. 6th Meeting of the Doctoral Students from Innsbruck’s Medical University and Life Sciences Disciplines, 24 November 2010, Innsbruck, Austria.
  5. 2nd Annual Meeting for Life Sciences, 24–25 September 2010, Igls, Tyrol, Austria.
  6. Joint Meeting of the Austrian and German Pharmaceutical Societies, 20–23 September 2011, Innsbruck, Austria.
  7. 3rd International Conference on Drug Discovery and Therapy (ICDDT), 7–10 February 2011, Dubai, UAE.
  8. 7th Meeting of the Doctoral Students from Innsbruck’s Medical University and Life Sciences Disciplines, 11 November 2011, Innsbruck, Austria.
  9. 17th International Pharmacy Conference & Exhibition, 19–21 September 2012, Islamabad, Pakistan.
  10. 9th Biennial International Conference of Pakistan Society for Microbiology, 28–31 January 2013, Karachi, Pakistan.
  11. Engaging Private Pharmacies in TB Care & Control - Training Workshop, 15 July 2013, Network of Development Professionals, Islamabad, Pakistan.
  12. 1st International Conference on Drug Development- Natural & Synthetic, 25–27 August 2013, COMSATS, Abbottabad, Pakistan.
  13. International Symposium on Nanomaterials: "Nanomaterials – Potential Applications & Challenges," 31 October 2013, Lahore University of Management Sciences, Lahore, Pakistan.
  14. 18th International Pharmacy Conference & Exhibition, 31 October – 2 November 2013, Pakistan Pharmacist Association, Lahore, Pakistan.
  15. Promoting Research and Publication in Pharmaceutical Policy and Practice, 20 December 2013, Health Services Academy, Islamabad, Pakistan.
  16. Recent Advances in Nanotechnology, 6 January 2014, PINSAT, Preston University, Islamabad, Pakistan.
  17. For Women in Science Week, 16–20 March 2014, UNESCO Headquarters, Paris, France.
  18. Good Governance for Medicines (GGM), 21–23 April 2014, World Health Organization, Lahore, Pakistan.
  19. Pharmaceutical Sector Assessment Survey - Level II, 15–17 September 2014, World Health Organization, Islamabad, Pakistan.
  20. 2nd International Workshop on Pharmacy Practice/Clinical Pharmacy, 15–19 December 2014, Quaid-i-Azam University, Islamabad, Pakistan.
  21. Sixth Structural Biology & Molecular Biophysics Workshop, 9 July 2015, University of Nebraska Medical Center (UNMC), Durham Research Center, Omaha, USA.
  22. Seminar on "Adventures in the Small World: A Novel Approach to Understanding Intracellular Events During HIV-1 Infection of the CNS," 17 July 2015, UNMC, Eppley Science Hall, Omaha, USA.
  23. Seminar on "Hybridtides and the Artisan Biology Platform - Towards Oral Delivery and Novel Therapeutic Mechanisms," 28 July 2015, UNMC, Durham Research Center, Omaha, USA.
  24. International Nanomedicines Symposium on Nanotheranostics, 26 November 2015, NORI, Islamabad, Pakistan.
  25. International Symposium on Nanomedicines: Development, Testing and Application Possibilities, 1 March 2016, NORI, Islamabad, Pakistan.
  26. ISESCO Women in Science Conference: "Contributions of Pakistani Women in Scientific and Social Development," 8 March 2016, Quaid-i-Azam University, Islamabad, Pakistan.
  27. Regional Workshop on Biosafety and Biosecurity for Life Sciences Researchers, 26–27 April 2016, Pakistan Academy of Sciences, Islamabad, Pakistan.
  28. 3rd Conference on Frontiers of Nanoscience and Nanotechnology, 25 October 2016, PINSTECH, Islamabad, Pakistan.
  29. 4th Conference on Frontiers of Nanoscience and Nanotechnology, 12–13 December 2017, PINSTECH, Islamabad, Pakistan.
  30. Research Protocol Development Workshop for Implementation Research, 9–12 May 2017, Health Services Academy, Islamabad, Pakistan.
  31. 2nd International Workshop on Experimental Biology (IWEB-2017): "Nanotheranostics: From Bench to Bedside and Beyond," 22–24 November 2017, NILOP, Islamabad, Pakistan.
  32. National Workshop on "Nanomedicine; Advancements and Challenges in Pakistan," 27–29 November 2017, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
  33. 1st Annual Health Research Conference: "Health Research- A Step towards Attaining SDGs 2030," September 2018, Pakistan Health Research Council (PHRC), Marriott Hotel, Islamabad, Pakistan.
  34. Regional Conference on Reinforce the Themes for Young University Lecturers and Professors on Counter-Radicalization, 30 June 2018, Center for Research and Security Studies, Hill View Hotel, Islamabad, Pakistan.
  35. 9th Annual Public Health Conference: "Global Public Health: Thinking Globally and Acting Locally," 4–5 December 2018, Pakistan Health Services Academy, Islamabad, Pakistan.
  36. National Dialogue on Women in Science, organized by UNESCO in partnership with UN Women, Pakistan Alliance for Maths and Science, and Lahore College for Women University (LCWU), 11–12 February 2019, LCWU, Lahore, Pakistan.
  37. 3rd International Conference on "Recent Advancement in Pharmaceutical Research and Drug Delivery," 19–20 February 2019, Quaid-i-Azam University, Islamabad, Pakistan.
  38. International "One-Health Research Symposium," Pakistan Academy of Sciences, 17 November 2019, Islamabad, Pakistan.
  39. International Conference and Workshop on "Dengue Infection in Pakistan and its Controlling Strategies," organized by the Department of Animal Sciences, Quaid-i-Azam University, 17 December 2019, Geo Auditorium, QAU, Islamabad, Pakistan.
  40. International Conference on Health and Migration, organized by the Department of Sociology in collaboration with Edinburgh University (UK) and International Centre for Migration Policy Development, 19 December 2019, Earth Sciences Auditorium, Islamabad, Pakistan.
  41. World Antimicrobial Awareness Week, 18–24 November 2020, Quaid-i-Azam University, Islamabad, Pakistan.
  42. 6th International Conference on Public Health (ICOPH 2020), 9–11 July 2020, Bangkok, Thailand.
  43. 4th International Conference on "Integrative Multidisciplinary Nanomedicine: A Game-Changing Strategy for Emerging Infectious Disease," 10 October 2020, Quaid-i-Azam University, Islamabad, Pakistan.
  44. Fighting Breast Cancer in a Developing Country: "Insight from Pink Pakistan Trust’s Technology-Driven Initiatives," 8 March 2021, COMSTECH Secretariat, Islamabad, Pakistan.
  45. Launch of ISAAA Brief 55 and Seminar on "Science Communication and Public Engagement," 9 March 2021, COMSTECH Secretariat, Islamabad, Pakistan.
  46. Workshop on "Nanomedicine – Development and Challenges," 15–17 March 2021, COMSTECH Secretariat, Islamabad, Pakistan.

 

  1. Comparative Bioavailability & Pharmacokinetic Characterization:

    • Explored the potential of self-nanoemulsifying drug delivery systems to enhance the bioavailability of phenothiazines.

  2. Nanoparticles Based on Thiolated Polymeric Excipients:

    • Developed innovative nanoparticle formulations using thiolated polymers to target amphotericin B to Leishmania parasites.

  3. Mucoadhesive In Situ Gel:

    • Designed a novel mucoadhesive in situ gel formulation using thiolated excipients for targeted drug delivery to the site of infection.

  4. Monocyte-Macrophage as Targeted Drug Depots:

    • Explored the potential of monocyte-macrophages as drug carriers for sustained drug release and targeted delivery to infection sites.

  5. Polyethyleneimine-g-Poly(caprolactone-co-lactic acid):

    • Synthesized and characterized a novel polymeric system for controlled drug release.
    • The aim was to optimize drug release kinetics and improve therapeutic outcomes.

  6. Polyethyleneimine-g-Chitosan Nanoparticles:

    • Developed nanoparticle formulations using polyethyleneimine-g-chitosan for efficient drug delivery.

  7. Mannose-Anchored Thiolated Nanocarriers:

    • Designed targeted nanocarriers using mannose as a targeting ligand to improve oral bioavailability of amphotericin B.
    • This research aims to overcome the oral bioavailability limitations of amphotericin B and improve patient compliance.

  8. Mannose-Anchored Thiolated Nanocarriers for Leishmaniasis:

    • Developed targeted nanocarriers for Leishmaniasis therapy, utilizing mannose as a targeting ligand to enhance drug delivery to infected cells.

  9. Disulfide Cross-Linked Multifunctional In Situ Gelling Cargo:

    • Synthesized a novel multifunctional in situ gelling system for oral peptide drug delivery.
    • This research aims to overcome the challenges associated with oral peptide delivery and improve therapeutic outcomes.

  10. Thiolated Polymer Coated Gel:

  • Developed a thiolated polymer-coated gel for controlled and targeted drug delivery in Leishmaniasis.
  1. Doped Phototoxic Nanoparticles-Based Topical Skin-Care Cream:
  • Developed a novel topical formulation using doped phototoxic nanoparticles as a potential treatment for Leishmania infection.

Quaid-i-Azam University Islamabad, 45320, Pakistan.
Tel: +92-51 9064 0000, Email:webmaster@qau.edu.pk