Research Interests

Elucidation of gene regulatory networks for early developmental regulators in

animals by employing computational and functional approaches.

Evolution of gene families and genomes.

Disease relevance of human non-coding sequences.

Abbasi A.A*, Hanif H (2012). Phylogenetic history of paralogous gene

quartets on human chromosomes 1, 2, 8 and 20 provides no

evidence in favor of the vertebrate octoploidy hypothesis,

Molecular Phylogenetics and Evolution (2012),

doi:10.1016/j.ympev.2012.02.028 *Corresponding Author

Abbasi A.A.*, (2011) Molecular evolution of HR, a gene that regulates

the postnatal cycle of the hair follicle. Sci. Rep. 1, 32;

DOI:10.1038/srep00032. wwwnature.com/scientificreports

*Corresponding Author

Abbasi A.A.*, (2011) Evolution of vertebrate appendicular structures: Insight

from genetic and palaeontological data. Developmental Dynamics,

240:1005-1066. (Special issue on limb development)

*Corresponding Author

Abbasi A.A.*, (2010) Unraveling ancient segmental duplication events in human

genome by phylogenetic analysis of multigene families residing on

HOX cluster paralogons. Molecular Phylogenetics and Evolution.,

57: 836-848. *Corresponding Author

Abbasi A.A*, Paparidis Z, Malik S, Bangs F, Schmidt A, Koch S, Lopez-Rios J,

Grzeschik KH (2010): Human Intronic Enhancers Control Distinct Sub-

domain of Gli3 Expression during Mouse CNS and Limb Development.

BMC Developmental Biology. 2010, 10:44.

(Highly accessed) .*Corresponding Author

Abbasi A.A.*, (2010) Piecemeal or big bangs: correlating the vertebrate

evolution with proposed models of gene expansion events. Nat Rev

Gene 11(2):166. *Corresponding Author

Abbasi A.A*, Goode DK, Amir S, Grzeschik KH (2009). Evolution and

functional diversification of the GLI family of transcription factors in

vertebrates. Evolutionary Bioinformatics 5: 5-13.

*Corresponding Author

Abbasi A.A*., (2008) Are we degenerate tetraploids? More genomes,

new facts. Biology Direct 3:50 (Highly accessed).

*Corresponding Author

Abbasi A.A*, Grzeschik KH (2007) An insight into the phylogenetic history of HOX linked gene families in vertebrates. BMC Evol Biol 7:239. *Corresponding Author

Abbasi A.A., Paparidis Z, Malik S, Goode DK, Callaway H, Elgar G, Grzeschik KH (2007) Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers. PLoS ONE 2:e366

Paparidis Z, Abbasi A.A., Malik S, Goode DK, Callaway H, Elgar G, deGraaff E, Lopez-Rios J, Zeller R, Grzeschik KH (2007) Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression. Dev Growth Differ 49:543-53

Malik S, Abbasi A.A, Ansar M, Ahmad W, Koch MC, Grzeschik KH (2006) Genetic heterogeneity of synpolydactyly: a novel locus SPD3 maps to chromosome 14q11.2-q12. Clin Genet 69:518-24

Wajid M, Abbasi A.A, Ansar M, Pham TL, Yan K, Haque S, Ahmad W, Leal SM (2003) DFNB39, a recessive form of sensorineural hearing impairment, maps to chromosome 7q11.22-q21.12. Eur J Hum Genet 11:812-5